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目的观察中药内服结合外敷治疗原发性肝癌腹水的临床疗效。方法将60例脾虚血瘀型原发性肝癌腹水患者随机分为治疗组和对照组,各30例。对照组口服安体舒通,治疗组采用健脾活血利水内服方及逐水药外敷,疗程均为15天。观察两组腹水、生活质量、中医症状改善情况。结果治疗组腹水的改善优于对照组(P<0.05);治疗后治疗组Karnofsky评分较治疗前提高(P<0.05),对照组降低(P<0.05);两组治疗前后差值比较有统计学意义(P<0.05);治疗后治疗组患者腹胀、腹痛等症状明显改善(P<0.05),且较对照组改善显著(P<0.05)。结论中药内服结合外敷治疗原发性肝癌腹水疗效显著,并可改善临床症状,提高患者生活质量。
Objective To observe the clinical efficacy of oral administration of traditional Chinese medicine combined with external application in the treatment of ascites of primary liver cancer. Methods Sixty cases of primary liver cancer with ascites due to spleen deficiency and blood stasis were randomly divided into treatment group and control group, with 30 cases in each group. In the control group, spironolactone was given orally. The treatment group was treated with Spleen and Huoxue Lihuizhu Oral and topical water-based drugs for 15 days. Observation of two groups of ascites, quality of life, improve the symptoms of Chinese medicine. Results The improvement of ascites in the treatment group was better than that in the control group (P <0.05). The Karnofsky score of the treatment group was significantly higher than that before treatment (P <0.05), while the control group was lower (P <0.05) (P <0.05). After treatment, the symptoms such as abdominal distension, abdominal pain and other symptoms in the treatment group were significantly improved (P <0.05), and significantly improved compared with the control group (P <0.05). Conclusion Chinese medicine combined with external application of topical treatment of primary liver cancer ascites significant effect, and can improve clinical symptoms and improve patient quality of life.