甲型血友病是一种表现为Ⅷ因子缺乏的X连锁的遗传性凝血机制障碍性疾病。关节积血是严重血友病患者最常见的表现之一,其中膝关节受累约占44%。血友病患者关节内反复出血及出血倾向可导致关节腔内积血发生机化,关节间隙狭窄甚至消失,对软骨的侵蚀可导致患者关节面的破坏,进而可导致膝关节严重的屈曲畸形。对于严重膝 Hemophilia A is a disorder of the X-linked hereditary coagulopathies characterized by a deficiency of factor VIII. Arterial hemorrhage is one of the most common manifestations of severe hemophilia, with about 44% of knee involvement. Hemophilia patients with repeated bleeding and bleeding within the joints tend to lead to hematoma joint articular cavities, narrow or even disappear joint space, the erosion of cartilage can lead to the destruction of the articular surface of patients, which can lead to severe knee flexion deformity. For severe knee