用吡喹酮对237例华支睾吸虫病患者进行治疗观察,并以六氯对二甲苯治疗40例作为对比。治后4个月复查表明,吡喹酮总剂量120毫克/公斤组的粪虫卵阴转率达97.1％,显著高于六氯对二甲苯组。治后患者症状及体征均有所改善。药物反应以吡喹酮治疗组轻。与六氯对二甲苯相比,吡喹酮疗程短,反应轻,疗效亦佳,是值得推荐的新药。 237 cases of clonorchiasis were treated with praziquantel, and 40 cases were treated with p-xylene. A review of 4 months after the treatment showed that the total fecal insects egg negative conversion rate of the praziquantel 120 mg / kg group was 97.1%, significantly higher than that of the hexachloro paraxylylene group. After treatment, symptoms and signs of patients have been improved. Drug response to praziquantel treatment group light. Compared with hexachloroparaxylylene, praziquantel treatment is short, the reaction is light, the curative effect is also good, is worth recommending new drug.