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电压门控的钠通道是拟除虫菊酯 (Pyrethroid)和滴滴涕 (dichloro diphenyl trichloroethane)的共同靶变点 ,是它们产生交互抗性 (击倒抗性 ,Knockdownresistance)的基础。由于拟除虫菊酯具有对昆虫和其他无脊椎动物呈高毒性 ,而对哺乳动物呈低毒性等特点 ,研究拟除虫菊酯的杀虫和抗药性机理 ,无论对人畜中毒的防治 ,还是对农业害虫的治理都有极为重大的意义
Voltage-gated sodium channels are a common target point of change for pyrethroid and dichloro diphenyl trichloroethane and are the basis for their mutual resistance (Knockdown resistance). Since pyrethroid has the characteristics of high toxicity to insects and other invertebrates and low toxicity to mammals, the pyrethroid insecticide and drug resistance mechanism is studied. Whether for the prevention and control of human and animal poisoning or for the development of agricultural pests Governance has a very significant meaning