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本研究目的是评价胆管癌神经束膜侵犯对预后的影响。1979～1990年期间共切除胆管癌94例,仅对其中70例进行分析。病人平均年龄57岁(32～82岁),男48例,女22例。本文所指的肝门癌包括肝总管、左右肝管,以及中下段胆管癌,乏特氏乳头和胆囊癌则除外.切除手术计胆管切除2例、肝切除和胆管切除46例、胰十二指肠切除8例和肝胰十二指肠切除4例。切除标本均作病理检查,计算至少3个部位的神经束膜受侵的情况。神经束膜侵犯指数(PNI)按下列公式计算:
The purpose of this study was to evaluate the effect of perineuricular invasion on the prognosis of cholangiocarcinoma. From 1979 to 1990, 94 cases of cholangiocarcinoma were removed, and only 70 of them were analyzed. The average age of the patients was 57 years old (32-82 years old), 48 males and 22 females. Hepatocellular carcinoma as referred to herein includes the common hepatic duct, the left and right hepatic ducts, and the middle and lower cholangiocarcinoma, except for the Vater’s nipple and gallbladder carcinoma. There are 2 cases of bile duct resection, 46 cases of hepatectomy and biliary resection, and 12 cases of pancreatic duct. Eight patients had intestinal resection and 4 had hepato-pancreatoduodenectomy. Resection specimens were all pathological examinations, and at least 3 sites of perineurium membrane invasion were calculated. Peritonal membrane invasion index (PNI) is calculated according to the following formula: