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将15只雄性家兔的两侧睾丸摘除,去势后一个月给动物静脉注射内毒素,复制发热模型,实验组动物施以电针,比较实验组及对照组动物的发热高峰(△T)和体温反应指数(TRI),前者差异性显著,后者差异性不显著。血浆睾酮水平与去势前比较,虽有降低但无统计学意义,而血浆雌二醇水平较去势前有明显增加,两者比较其差异性显著。去势后三个月,血浆睾酮水平较去势前有明显减少,去势前和去势后两者相比较其差异性显著。血浆雌二醇水平进一步增加,与去势前比较其差异性非常显著。去势后三个月开始给动物肌肉注射戊酸雌二醇,每天一次连续11天。然后再用内毒素复制发热模型,实验组施以电针,比较两组动物的△T和TRI,其差异性均显著,结果表明针刺抑制动物体温上升和血浆性激素水平有关。
The testes of the two male rabbits were excised on both sides. The animals were given endotoxin intravenously one month after castration. The febrile animal models were replicated. Electroacupuncture was applied to animals in the experimental group to compare the peaks of fever (△T) between the experimental group and the control group. And the body temperature reaction index (TRI), the former significant difference, the latter difference is not significant. Although plasma testosterone level was lower than before castration, it was not statistically significant, but plasma estradiol level was significantly increased before castration. There was a significant difference between the two groups. Three months after castration, plasma testosterone levels were significantly lower than those before castration. There was a significant difference between the two before and after castration. Plasma estradiol levels further increased, and the difference was significant compared with before castration. Three months after castration, animals were injected intramuscularly with estradiol valerate once daily for 11 consecutive days. Then endotoxin was used to replicate the febrile model. Electroacupuncture was applied to the experimental group to compare the △T and TRI of the two groups. The difference was significant. The results showed that acupuncture inhibited the increase of body temperature and plasma sex hormone levels.