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目的探讨双源64层CT(DSCT)和血管内超声(IVUS)识别冠状动脉易损斑块(VP)的价值。方法经冠状动脉造影(CAG)确诊的冠心病患者58例,CAG前1周内行DSCT冠状动脉造影检查,CAG后行IVUS检查。与IVUS比较,评价DSCT诊断冠状动脉VP的敏感性、特异性、准确性。同时评价两种方法测量最大斑块面积的相关性。结果与IVUS比较,DSCT识别VP的敏感性、特异性分别为89.7%、96.4%,阳性预测值和阴性预测值分别为85.4%、97.6%。DSCT和IVUS测定的斑块平均面积分别为(9.21±4.35)mm2和(9.41±3.96)mm2。两种方法对斑块面积的测量差异无统计学意义(r=0.87,P>0.05)。结论 DSCT与IVUS相似,对识别冠状动脉VP有较好的价值。
Objective To investigate the value of dual-source 64-slice CT (DSCT) and intravascular ultrasound (IVUS) in identifying vulnerable plaque of coronary artery (VP). Methods Fifty-eight patients with coronary heart disease confirmed by coronary angiography (CAG) were undergone DSCT coronary angiography one week before CAG and IVUS after CAG. Compared with IVUS, evaluate the sensitivity, specificity and accuracy of DSCT in diagnosing coronary artery. The correlation between the two methods for measuring the largest plaque area was also evaluated. Results Compared with IVUS, the sensitivity and specificity of DSCT in recognizing VP were 89.7% and 96.4%, respectively. The positive predictive value and negative predictive value were 85.4% and 97.6% respectively. The average plaque area measured by DSCT and IVUS were (9.21 ± 4.35) mm2 and (9.41 ± 3.96) mm2, respectively. There was no significant difference between the two methods in the measurement of plaque area (r = 0.87, P> 0.05). Conclusions DSCT is similar to IVUS and has a good value in identifying coronary artery VP.