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探讨人脾脏突触体素、S- 10 0蛋白和 NSE免疫反应神经纤维的支配 ,为脾脏的神经免疫相互作用提供形态学资料。应用免疫组织化学 ABC法观察正常人脾脏 30例 ,福尔马林固定 ,石蜡包埋组织切片。结果显示突触体素、S- 10 0蛋白和 NSE免疫反应神经纤维呈细丝、串珠状 ,沿着脾血管的各级分支进入脾实质 ,主要沿着脾动脉的分支而分布 ,以中央动脉血管尤为丰富 ,它们分布在白髓、红髓和边缘区 ,穿行于淋巴细胞之间。人脾脏小梁中未查见免疫反应神经纤维。由此可提示人类脾脏有突触体素、S- 10 0蛋白、NSE免疫反应神经纤维的分布 ,为人类脾脏神经免疫相互作用提供了形态学资料。
To investigate the control of human spleen synaptophysin, S-10 protein and NSE immunoreactive nerve fibers, and to provide morphological data for the spleen’s neuroimmunity interaction. Immunohistochemical ABC method was used to observe the normal human spleen 30 cases, formalin fixed, paraffin-embedded tissue sections. The results showed that the synaptophysin, S-10 protein and NSE immunoreactive nerve fibers were filamentous and beaded, and branched into the spleen parenchyma at all levels along the splenic blood vessels, mainly distributed along the branches of the splenic artery. The central artery Blood vessels are particularly rich, they are distributed in white pulp, red pulp and marginal zone, walk through the lymphocytes. No immunoreactive nerve fibers were found in human spleen tracts. This can be prompted human spleen synaptophysin, S-10 0 protein, NSE immunoreactive nerve fiber distribution, for human spleen nerve-immune interaction provides morphological information.