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为了给深入开发利用大豆提供科学依据,采用含胆固醇1.0%,胆盐0.2%的饲料喂养SD大鼠,同时分别喂以6%的大豆纤维(SF)和纯纤维素,然后与只加胆固醇(Ch)和胆盐的高Ch组及正常饲料组对照,比较这两种纤维对血脂、血小板聚集性(PtA)和凝血时间(CgT)的影响。结果发现,SF不但能显著降低血清总胆固醇、低密度脂蛋白胆固醇(LDL-C)和动脉粥样硬化指数,增加高密度脂蛋白胆固醇(HDL-C)/TC比值,且能明显降低纤维蛋白原(Fb)含量和PtA,延长CgT。而纯纤维素组未显示以上作用。作者认为,SF的降脂作用是通过降低高脂动物血中LDL-C实现的。血脂和Fb的降低可能是SF膳食使动物PtA下降及CgT延长的主要原因
In order to provide a scientific basis for the further development and utilization of soybean, SD rats were fed with feed containing 1.0% cholesterol and 0.2% bile salt, while 6% soybean fiber (SF) and pure cellulose were fed respectively, Cholesterol (Ch) and bile salt alone were compared with those of the normal chow diet to compare the effects of these two fibers on blood lipids, platelet aggregation (PtA) and clotting time (CgT). The results showed that SF not only significantly reduced serum total cholesterol, low density lipoprotein cholesterol (LDL-C) and atherosclerosis index, increased the ratio of high-density lipoprotein cholesterol (HDL-C) / TC, and significantly reduced fibrin Original (Fb) content and PtA, extend CgT. The pure cellulose group did not show the above effect. The authors believe that the lipid-lowering effect of SF is achieved by reducing LDL-C in the blood of hyperlipidemic animals. The decrease of blood lipids and Fb may be the main reason for the decrease of PtA and the prolongation of CgT in SF diet