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对以猕猴桃汁、绞股蓝、丹参和其他中药配制的保健药(大自然健身滋)进行急性和长期毒性试验。测得小鼠和大鼠的经口LD50均大于6g/kgB.W.(相当人每日剂量的100倍),大鼠连续灌服本制剂(大剂量组每日剂量相当于人每日剂量50倍)45、90天,体重增长,无中毒表现,肝、肾功能及血常规检查无异常,处死后作病理检查,各主要脏器未见病变。
Acute and long-term toxicity tests were conducted on health-care medicine (Nature Fitness) formulated with kiwifruit juice, Gynostemma pentaphyllum, Salvia miltiorrhiza and other Chinese medicines. The oral LD50 of both mice and rats was greater than 6g/kg B.W. (100 times the daily dose of humans), and the rats were continuously fed with this preparation (high-dose group daily dose equivalent to human daily dose 50 times) 45, 90 days, weight gain, no poisoning performance, liver, kidney function, and blood routine examinations were not abnormal. After being sacrificed for pathological examination, no major lesions were seen in all major organs.