论文部分内容阅读
目的:神经母细胞瘤是新生儿最常见的一种肿瘤。本研究回顾了被确诊患局限性神经母细胞瘤的新生儿的临床特征、治疗和结局。研究对象和方法:分析了1990-1999年间法国18个小儿肿瘤中心按照1990年和1994年拟定的神经母细胞瘤(NBL)治疗方案进行救治的52例患者的数据。结果:患儿年龄的中位数是12 d (年龄范围0-28 d),其中14例(27%)在产前检查时确诊。肿瘤发生部位有40例在腹部(其中20例在肾上腺附近),8例位于胸部,3例在盆腔,还有1例位于子宫
Purpose: Neuroblastoma is one of the most common neoplasms in newborns. This study reviews the clinical features, treatment, and outcome of neonates diagnosed with localized neuroblastoma. PARTICIPANTS AND METHODS: Data were analyzed for 52 patients treated in France’s 18 pediatric oncology centers between 1990 and 1999 in accordance with the neuroblastoma (NBL) regimen developed in 1990 and 1994. Results: The median age of children was 12 days (range, 0-28 days) and 14 (27%) were diagnosed at prenatal care. Tumor sites were 40 in the abdomen (20 of which were near the adrenal gland), 8 in the chest, 3 in the pelvis, and 1 in the uterus