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目的:探讨血管性帕金森综合征(VP)的临床特点,并与原发性帕金森病(PD)相鉴别。方法:对20例VP患者的临床表现、实验室检查及影像学结果进行回顾性分析,并与93例PD患者的临床资料进行对比。结果:VP患者多数有高血压、糖尿病史;影像学改变以皮质下白质、基底节多发腔隙性梗死为主。结论:VP发病年龄较高,影像学改变主要以皮质下白质、基底节多发腔隙性梗死为主,具有更多的脑血管病危险因素。
Objective: To investigate the clinical features of vascular Parkinson’s disease (VP) and differentiate it from primary Parkinson’s disease (PD). Methods: The clinical manifestations, laboratory findings and imaging findings of 20 patients with VP were retrospectively analyzed and compared with the clinical data of 93 patients with PD. Results: The majority of patients with hypertension had history of hypertension and diabetes. Imaging changes mainly included subcortical white matter and basal ganglia with multiple lacunar infarcts. Conclusion: The age of onset of VP is high. The main imaging changes are mainly subcortical white matter and basal ganglia with multiple lacunar infarcts, which have more risk factors of cerebrovascular disease.