目的:探讨肠易激综合征(IBS)患者的焦虑、抑郁及睡眠等特征,揭示其内在的关系。方法:选择45例IBS患者,同时随机选择45例健康体检者为对照组,采用焦虑量表(SAS)、抑郁量表(SDS)、匹兹堡睡眠质量指数量表(PSQI)对两组研究对象进行调查,比较两组患者的焦虑、抑郁、睡眠障碍患病率,以及睡眠质量评分。结果:IBS组的焦虑、抑郁、睡眠障碍患病率分别为28.9%、40.0%和48.9%,均高于对照组的8.9%、11.1%、17.8%(P<0.05);IBS组的睡眠质量、日间功能障碍、睡眠障碍、安眠药物等因子评分均高于对照组(P<0.01),而IBS组的入睡时间、睡眠时间及睡眠效率等因子评分与对照组相比则无统计学差异(P>0.05)。结论IBS患者存在较为严重的焦虑、抑郁、睡眠障碍,而且IBS组的整体睡眠质量比健康人群差,临床治疗过程中应进行综合干预。 Objective: To investigate the characteristics of anxiety, depression and sleep in patients with irritable bowel syndrome (IBS) and to reveal its intrinsic relationship. Methods: Forty-five patients with IBS were selected and 45 healthy subjects were randomly selected as the control group. SAS, SDS and PSQI were used to compare the two groups Investigations were conducted to compare anxiety, depression, prevalence of sleep disorders, and sleep quality scores for both groups. Results: The prevalence rates of anxiety, depression and sleep disturbance in IBS group were 28.9%, 40.0% and 48.9% respectively, which were all higher than those in control group (8.9%, 11.1%, 17.8%, P <0.05) , Daytime dysfunction, sleep disorders, hypnotherapy and other factors were higher than the control group (P <0.01), while the IBS group fell into sleep time, sleep time and sleep efficiency factor scores compared with the control group, there was no significant difference (P> 0.05). Conclusions The patients with IBS have more serious anxiety, depression and sleep disorders, and the overall quality of sleep in IBS patients is worse than that in healthy people. Comprehensive intervention should be carried out during the course of clinical treatment.