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晚期卵巢癌约50%~70%有淋巴结转移,但其对预后的影响尚不清楚。为分析晚期卵巢癌患者淋巴结受侵对预后的影响,对首次组织学诊断证实为浸润性的上皮性卵巢癌,FICA3分期Ⅲ~Ⅳ期,年龄<75岁,按照美国东部地区肿瘤协作组的病人体力状况评分为0,1或2,无其他恶性肿瘤病史及心脏病史,既往无化疗、放疗史的456例卵巢癌患者进行随机临床研究,对Ⅲ~Ⅳ期卵巢癌患者行选择性盆腔和/或腹主动脉旁淋巴结切除及肿瘤细胞减灭术后,再给以顺铂为基础的联合化疗两种方案进行比较分析。患者均按标准方式行肿瘤细胞减灭术,术
About 50% to 70% of advanced ovarian cancer have lymph node metastasis, but its impact on prognosis is not yet clear. In order to analyze the prognosis of advanced ovarian cancer patients with lymph node invasion, the first histological diagnosis of invasive epithelial ovarian cancer, FICA3 stage Ⅲ ~ Ⅳ, age <75 years, according to the United States Eastern Cooperative Oncology Group patients Physical status score of 0, 1 or 2, no other malignancy and history of heart disease, no history of chemotherapy and radiotherapy in 456 cases of ovarian cancer patients for randomized clinical study of patients with stage Ⅲ ~ Ⅳ ovarian cancer patients with selective pelvic and / Or para-aortic lymph node dissection and tumor cytoreductive surgery, and then to cisplatin-based combination chemotherapy two programs for comparative analysis. Patients were treated by standard cytoreductive surgery, surgery