随着基础免疫学的发展,对牙周组织的免疫反应的研究日趋活跃。厌氧菌培养与测定的确立,通过牙周病病原菌的研究,阐明了牙周病的发生、发展与特定菌种密切相关。作者在临床研究中应用牙周袋内的螺旋体诊断牙周病取得了新成果。螺旋体广泛生息在与牙周病发生、 With the development of basic immunology, the immune response to periodontal tissues is becoming more and more active. Anaerobic bacteria culture and determination of the establishment of periodontal disease pathogens through clarification of the occurrence of periodontal disease, development and specific species are closely related. The authors have achieved new results in the clinical study of periodontal disease diagnosed with spirochetes in the periodontal pocket. Spirochaete widely occurs with periodontal disease occurs,