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芳基末端炔是一类重要的有机合成中间体,在众多领域具有广泛的应用,其合成备受广大研究者的高度关注。本文阐述了末端炔的合成研究进展,着重综述了近十年来芳基末端炔合成发展情况,包括分别以卤代烯烃、卤代芳烃、芳醛等为原料的末端炔的合成方法。文章还对一些方法的应用做了介绍,并对重要反应机理作了分析,最后对该类化合物的合成情况进行了总结并展望了未来发展方向。
Aryl terminal alkynes are an important class of organic synthesis intermediates and have been widely used in many fields. Their synthesis has attracted a great deal of attention from researchers. In this paper, the progress in the synthesis of terminal alkynes is reviewed. The development of aryl terminal alkyne synthesis in recent ten years is reviewed, including the synthesis of terminal alkynes using halogenated olefins, halogenated aromatic hydrocarbons and aromatic aldehydes as raw materials respectively. The article also introduces the application of some methods and analyzes the important reaction mechanism. Finally, the synthesis of these compounds is summarized and the future development direction is forecasted.