内膜异位症常发生于育龄妇女并可引致不育,对其病因尚有争议。虽已提出多种机制以说明内膜异位症引致的不育,但目前尚无定论。不论用何种方法,用腹腔镜诊断之后总伴有妊娠率增加,提示腹腔镜诊断可能起到某种治疗作用。尽管其作用机制尚未弄清,但可预料的因素有:腹腔镜操作,抽吸腹腔液,扩张宫颈管及/或输卵管灌洗。本工作试图阐明内膜异位症伴随不育的机制,提出的假设为:在内膜异位症的腹腔液中,存在一种抑制输卵管伞端摄取和转运卵子的因子。作者从7～8周的雌性金黄色地鼠得到输卵管及输卵管伞端。给4周的未成年雌性ICR小鼠腹腔注射孕马血清促性腺激素及hCG以得到小鼠的卵母细胞-卵丘复合物。用体外实验观察内膜异位症 Endometriosis often occurs in women of childbearing age and can lead to infertility, the cause is controversial. Although a variety of mechanisms have been proposed to explain infertility caused by endometriosis, it is inconclusive. Regardless of the method used, with laparoscopic diagnosis of the total increased pregnancy rate, suggesting that laparoscopic diagnosis may play a therapeutic role. Although the mechanism of action is unclear, predictable factors include laparoscopic operation, aspiration of the peritoneal fluid, expansion of the cervical canal, and / or tubal lavage. This work attempts to elucidate the mechanism of endometriosis associated with infertility, made the assumption that: In the peritoneal fluid of endometriosis, there is a factor that inhibits tubal umbrella side of the transfer and transfer of eggs. The authors received tubal and fallopian tube ends from female golden hamsters for 7-8 weeks. Four-week-old female ICR mice were intraperitoneally injected with mare serum gonadotropin and hCG to obtain mouse oocyte-cumulus complex. In vitro experimental observation of endometriosis