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本文用甲苯胺蓝染色法对甲基胆蒽诱发的小鼠宫颈鳞癌间质中肥大细胞的分布进行了观察。结果表明,肥大细胞主要分布在癌旁间质和深层间质。癌间质中数量少(P<0.05),颗粒稀疏,并有明显脱颗粒现象。我们认为,癌间质中肥大细胞数量少是由于肥大细胞脱颗粒的结果,是肥大细胞功能状态的一种形态学表现,并非肥大细胞数量的真正减少。
In this paper, toluidine blue staining of methylchole anthracene-induced mouse cervical squamous cell stroma in the distribution of mast cells were observed. The results showed that mast cells are mainly distributed in the paracancerous and deep stroma. The number of cancer interstitial less (P <0.05), sparse particles, and significant degranulation. We believe that the small number of mast cells in the cancerous stroma is a result of mast cell degranulation and is a morphological manifestation of the functional status of mast cells and not a true reduction in the number of mast cells.