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目的:研究百合固金口服液联合N-乙酰半胱氨酸(NAC)对慢性阻塞性肺疾病(COPD)稳定期患者疗效;方法:80例COPD稳定期患者随机分为观察组和对照组各40例。对照组采用西医常规治疗方法。观察组采用百合固金口服液联合NAC;观察2组治疗前后慢性阻塞性肺疾病自我评估测试(CAT)评分及肺功能。结果:2组治疗前后CAT评分有改善,治疗后评分均小于治疗前评分,治疗前后CAT评分差≥2分(P<0.05),观察组CAT评分差≥4分减少更明显(P<0.05);2组肺功能FEV1/FVC变化不明显(P>0.05),FEV1有改善(P<0.05);观察组的用力呼气流量(FEF25%~75%)有显著改善(P<0.01)。结论:百合固金口服液联合N-乙酰半胱氨酸治疗能改善慢性阻塞性肺疾病稳定期患者临床症状及肺功能。
Objective: To study the curative effect of Lily Ginkgo oral solution combined with N-acetylcysteine (NAC) on patients with chronic obstructive pulmonary disease (COPD) in stable phase.Methods: Eighty patients with stable COPD were randomly divided into observation group and control group 40 cases. The control group adopted the conventional treatment of Western medicine. The observation group was treated with Lily Ginkgo oral solution combined with NAC. The CAT score and pulmonary function of the two groups before and after treatment were observed. Results: Before and after treatment, the CAT score was improved in both groups. After treatment, the scores were less than those before treatment. The CAT scores were worse than or equal to 2 before and after treatment (P <0.05) ; FEV1 / FVC was not significantly changed (P> 0.05), FEV1 was improved in the two groups (P <0.05); forced expiratory flow (FEF25% ~ 75%) in the observation group was significantly improved (P <0.01). Conclusion: Lily Ginkgo oral solution combined with N-acetylcysteine can improve clinical symptoms and lung function in patients with chronic obstructive pulmonary disease.