感染性休克属严重脓毒症,是引起ICU患儿病死的主要原因。糖皮质激素用于治疗感染性休克已有多年。但对糖皮质激素使用的指征、剂量及疗程却一直存在不同看法。本文对糖皮质激素治疗感染性休克的相关问题进行讨论。1感染性休克与肾上腺皮质功能不全1.1病理生理[1]严重的感染可激 Septic shock is a severe sepsis and is the leading cause of death in children with ICU. Glucocorticoids have been used for the treatment of septic shock for many years. However, indications for glucocorticoid use, dosage and duration of treatment have been different. This article discusses the issues related to the treatment of septic shock with glucocorticoids. 1 septic shock and adrenal insufficiency 1.1 Pathophysiology [1] Serious infection can be stimulated