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目的：观察纳洛酮治疗耳鸣的疗效。方法：耳外伤后耳鸣３０例５３耳（男性１６例，女性１４例，年龄３６±ｓ６ａ）为纳洛酮组，在常规治疗药物的同时，加用纳洛酮０．８ｍｇ，溶于５％葡萄糖氯化钠注射液２５０ｍＬ，静脉滴注，ｑｄ，１３ｄ为一个疗程，停药７ｄ，重复一个疗程。对照组２８例４８耳（男性１５例，女性１３例，年龄３６±５ａ）仅作常规治疗。结果：纳洛酮组痊愈率（５１％）高于对照组（２９％）（Ｐ＜０．０５）。未发现不良反应。结论：纳洛酮治疗耳鸣有效。
Objective: To observe the curative effect of naloxone on tinnitus. Methods: Tinnitus of 30 cases (46 males and 14 females, age 36 ± s6a) were treated with naloxone in the group of tinnitus. The naloxone group was treated with 0.8 mg naloxone and dissolved in 5% Glucose sodium chloride injection 250mL, intravenous infusion, qd, 13d for a course of treatment, withdrawal 7d, repeat a course of treatment. In control group, 28 cases (48 males and 15 females, 13 females, age 36 ± 5a) were treated only routinely. Results: The cure rate of naloxone group (51%) was higher than that of control group (29%) (P <0.05). No adverse reactions found. Conclusion: Naloxone is effective in treating tinnitus.