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目的探讨养血生乳口服液对妇女产后子宫缩复和免疫功能的影响。方法采用单盲随机对照法,以产宝口服液为对照,对正常产妇117例进行临床观察;通过实验观察养血生乳口服液对产后小鼠离体子宫平滑肌的影响,并采用环磷酰胺制造小鼠免疫抑制模型,观察了其对小鼠腹腔巨噬细胞吞噬功能和T细胞数的影响。结果养血生乳口服液能明显促进妇女产后子宫缩复,减少产后出血量,增强产妇免疫功能;并能显著增加产后小鼠离体子宫平滑肌的收缩张力和收缩频率,明显提高免疫抑制小鼠巨噬细胞吞噬功能和增加T细胞数。结论养血生乳口服液有较好的促进妇女产后康复作用,其机制可能与其提高子宫收缩作用和增强免疫功能有关。
Objective To investigate the effect of Yangxueshengei oral liquid on postpartum uterus contraction and immune function in women. Methods Single-blind randomized control method was used to compare the results of 117 cases of normal parturients with the production of Oral Liquid. The effects of Yangxueshengru oral liquid on uterine smooth muscles of postpartum mice were observed by experiments, and were made by cyclophosphamide. Mouse immunosuppressive model was used to observe its effect on phagocytic function and number of T cells in mouse peritoneal macrophages. Results Yangxue Shengri oral liquid can significantly promote postpartum uterine contraction in women, reduce postpartum hemorrhage, enhance maternal immune function, and can significantly increase the contractile tension and contraction frequency of isolated uterine smooth muscles in postpartum mice, and significantly improve immunosuppressive mice. Macrophages phagocytose and increase the number of T cells. [Conclusion] Yangxue Shengri Oral Liquid has a good effect on the postpartum rehabilitation of women, and its mechanism may be related to the increase of uterine contraction and enhancement of immune function.