论文部分内容阅读
利用木质纤维素生产燃料乙醇的过程中,前期预处理所产生的抑制剂会影响酵母的正常生长和后续的发酵过程。为减小抑制剂的影响所采取的一些脱毒策略往往造成糖的损失和生产成本的增加,这在实际生产与经济上是不可行的。因此,具有强的抑制剂耐受性的酿酒酵母菌株对于提高纤维素乙醇产率是十分重要的。近十年来,对于酿酒酵母胁迫耐受机制的研究取得了一些重要的进展,着重介绍目前酿酒酵母对抑制剂耐受机制的研究现状,包括一些关键性基因的表达及代谢通路过程分析等。同时也介绍一些应对抑制剂提高酵母发酵能力的措施。
In the process of using lignocellulose to produce fuel ethanol, the pretreatment produces inhibitors that affect the normal growth of the yeast and subsequent fermentation processes. Some detoxification strategies taken to reduce the effects of inhibitors often result in loss of sugar and increased costs of production, which are not practically feasible and economically viable. Therefore, S. cerevisiae strains with strong inhibitor tolerance are important for improving cellulosic ethanol yield. In the recent ten years, some important progresses have been made in stress tolerance mechanism of Saccharomyces cerevisiae. Emphasis is put on the current research status of Saccharomyces cerevisiae on the mechanism of inhibitor tolerance, including the expression of some key genes and the analysis of metabolic pathways. Some measures to deal with the ability of inhibitors to improve yeast fermentation are also presented.