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为了探讨PLA2、TNF与肺血管收缩、肺动脉高压形成的关系,作者建立了常压低氧大鼠肺动脉高压模型,观察这些物质的含量变化。将缺氧组大鼠放入常压缺氧舱内缺氧,缺氧期间舱内氧浓度控制在10%,每天缺氧8h,连续21d。缺氧结束后采用右心导管法检测血流动力学指标。包括肺动?
In order to investigate the relationship between PLA2, TNF and pulmonary vasoconstriction and pulmonary hypertension, the authors established a model of pulmonary hypertension in rats under normobaric hypoxia and observed the changes of these substances. The hypoxia rats were placed in hypoxia chamber under hypoxia. During hypoxia, the oxygen concentration in the chamber was controlled at 10%, hypoxia for 8 h everyday for 21 days. Right heart catheterization was used to detect the hemodynamic parameters after hypoxia. Including pulmonary motion?