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目的观察蒲元和胃胶囊治疗慢性非萎缩性胃炎的临床效果。方法选择慢性非萎缩性胃炎患者90例随机分为对照组和治疗组,两组合并幽门螺杆菌感染患者,给予根除治疗。治疗组给予蒲元和胃胶囊治疗,对照组给予安慰剂。结果治疗后两组临床症状、病理、幽门螺杆菌感染情况比较差异有统计学意义(P<0.05)。治疗组55例患者在服药过程中有4例出现大便干。合并幽门螺杆菌感染患者在根除幽门螺杆菌的治疗过程中治疗组和对照组分别有5例和3例出现纳差、口苦,停药后均消失。疗程结束后复查血常规、尿常规、肝肾功能、心电图、消化系统彩超等检查均无明显异常。结论蒲元和胃胶囊治疗慢性非萎缩性胃炎有效率高、不良反应小,同时可提高幽门螺杆菌的根除率。
Objective To observe the clinical effect of Pu Yuan He Wei Capsule in the treatment of chronic non-atrophic gastritis. Methods Ninety patients with chronic non-atrophic gastritis were randomly divided into control group and treatment group. Patients in two groups with H. pylori infection were given eradication therapy. The treatment group was treated with Puyuanhewei capsule and the control group with placebo. Results After treatment, the clinical symptoms, pathology, Helicobacter pylori infection in the two groups showed statistically significant difference (P <0.05). In the treatment group, 55 patients developed dry stool in 4 patients during medication. Helicobacter pylori infection in patients with eradication of Helicobacter pylori in the treatment group and control group were 5 cases and 3 cases of anorexia, mouth pain, after stopping all disappeared. After the end of treatment, blood routine examination, urinalysis, liver and kidney function, electrocardiogram, digestive system ultrasound and other tests showed no obvious abnormalities. Conclusion PU Yuanhewei Capsule is effective in treating chronic non-atrophic gastritis with small adverse reactions and can improve the eradication rate of Helicobacter pylori.