从纤维堆囊菌菌株So0157-2发酵吸附树脂的提取物中分离得到四个天然埃博霉素衍生物,包括两个14元环埃博霉素L(1)和L1(2),以及两个环氧环打开的埃博霉素A(3)和B(4)。并根据核磁共振和质谱等方法鉴定了它们的结构。这四个化合物都是首次作为天然产物从该菌株中分离得到,也是首次对化合物的数据进行全指定。 Four natural epothilone derivatives were isolated from extracts of the Fungus spp strain So0157-2 fermentative adsorption resin, including two 14-membered epothilone L (1) and L1 (2), and two Epoxy opened epothilone A (3) and B (4). Their structures were identified by methods such as nuclear magnetic resonance and mass spectrometry. All four compounds were isolated from this strain for the first time as a natural product, and for the first time, the data for the compounds were fully assigned.