尖锐湿疣主要是由 HPV_(6、11、16、18)型感染引起,不少病例可继发非典型性增生甚至癌变.本研究应用显微分光光度计对尖锐湿疣基底细胞、棘细胞核内 DNA进行定量测定,以探讨其非典型性增生及癌变情况.材料与方法一、标本来源和制备经临床和病理确诊的外阴尖锐湿疣20例,巨大尖锐湿疣5例.年龄18～40岁,病程2周～2年.对照组为正常外阴皮肤5例,粘膜5 Condyloma acuminatum is mainly caused by HPV_ (6, 11, 16, 18) infection, many cases may be secondary to atypical hyperplasia and even carcinogenesis.In this study, the use of micro-spectrophotometer of genital warts basal cells, To investigate the atypical hyperplasia and carcinogenesis.Materials and Methods1.Samples of origin and preparation of clinically and pathologically confirmed genital warts in 20 cases, 5 cases of huge condyloma acuminatum.Ages 18 to 40 years old, duration 2 Week ~ 2 years.The control group was normal vulvar skin in 5 cases, mucosa 5