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目的 :了解功能性消化不良 (functionaldyspepsia ,FD)患者胆囊排空功能 ,探讨胆囊运动与FD的关系。方法 :采用放射性核素显像法检测 2 6例功能性消化不良患者 (FD组 )空腹及试餐后胆囊排空 ,并与 2 1例正常成人 (NC组 )空腹及餐后胆囊排空作比较。结果 :FD组十二指肠显像时间为 43 2± 2 6min ,对照组为 2 5 7± 3 8min ;空腹及试餐后 40、5 0、6 0min胆囊排空分数明显低于正常对照组相应时相的胆囊排空分数 ,差异有显著性意义。结论 :FD患者存在胆囊排空障碍 ,考虑系胆囊收缩无力和Oddis括约肌运动不协调所致 ,提示胆囊排空障碍是功能性消化不良的病理生理基础和病因之一。
Objective: To understand the function of gallbladder emptying in patients with functional dyspepsia (FD) and to explore the relationship between gallbladder movement and FD. Methods: The fasting and postprandial gallbladder emptying in 26 patients with functional dyspepsia (FD group) was detected by radionuclide imaging and was compared with the emptying and postprandial gallbladder emptying of 21 normal adults (NC group) Compare Results: The duodenal imaging time was 43 2 ± 2 6min in FD group and 25 57 ± 3 8min in control group. The emptying time of gallbladder at 40, 50, 60min after fasting and after meals was significantly lower than that of normal control group The corresponding phase of the gallbladder emptying fraction, the difference was significant. Conclusion: FD patients with gallbladder emptying disorder, consider the Department of gallbladder contraction weakness and Oddis sphincter movement caused by uncoordinated, suggesting that gallbladder emptying dysfunction is one of the pathophysiological basis of functional dyspepsia.