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随着对新生儿及早产儿等呼吸衰竭治疗的进展,呼吸器与高压力高浓度氧输入已在临床广泛应用,使此类患儿存活率有了明显提高,与此同时,因进行氧治疗而产生的并发症——氧中毒的报导也日见增多。Northway等曾报导一组患严重肺透明膜病新生儿,于恢复期发生过一种慢性肺部疾患,称之为支气管肺发育不全(简称BPD),指出该组患儿均曾用过温暖湿化的高浓度(80～100%)氧、经间歇正压呼吸(IPPV)吸入达24小时以上,致使并发肺
With the progress of neonatal and premature infants and other respiratory failure treatment, respirators and high-pressure high-concentration oxygen has been widely used in clinical practice, so that such children have significantly improved the survival rate, at the same time, due to oxygen therapy Complications - reports of oxygen toxicity are also on the rise. Northway et al. Reported that a group of newborns with severe hyaline membrane disease had a chronic lung disease during convalescence called bronchopulmonary dysplasia (BPD), indicating that the group of children had been warm and wet The high concentration of oxygen (80-100%), intermittent positive pressure breathing (IPPV) inhalation for 24 hours or more, resulting in concurrent lung