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目的:筛选灵芝螺旋藻复合片直接制片的最佳配方。方法:采用正交设计实验,多指标(片型外观、片质量、硬度、脆碎度、崩解度)综合评分的方法。结果:经极差比较、方差分析和水平间多重比较,并结合实际生产应用,确定最佳配方。结论:该片剂配方合理,片剂成型质量好,片剂硬度适宜,片面光滑、完整、边缘正齐,制备工艺简单易行,适合现代企业大规模生产要求。
Objective: To screen the optimal formula of direct production of Ganoderma spirulina composite tablets. Methods: Orthogonal design experiment, multi-index (slice appearance, slice quality, hardness, friability, disintegration) comprehensive score method. Results: Through the comparison of range, variance analysis and multiple comparison between levels, combined with the actual production and application, to determine the best formula. Conclusion: The tablet formulation is reasonable, tablet forming quality is good, tablet hardness is suitable, smooth, complete, edge is homogeneous, the preparation process is simple and easy, suitable for large-scale production requirements of modern enterprises.