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据西雅图华盛顿大学一个研究小组报道:附睾炎可能是乙胺碘味酮疗法的一种副作用。1例42岁的男子,服用乙胺碘呋酮治疗室性心动过速,治疗后11个月发生左半阴囊触痛和附睾肿胀。尿分析、尿道吸引和配对血清未发现感染原因,而且生殖泌尿系没有解剖学上的异常。上述症状逐渐消失,但病人突因心血管病而死亡。死后发现附睾有纤维变性和淋巴细胞浸润. 此外,研究小组还审查56例连续服用乙胺碘呋酮的病历,其中6人(11%)阴囊疼痛并有附睾肿胀,超过6个月,发生率比预料的为高。6例病人平均年龄与其他病人相同,没有解剖上或感染的原因,但他们曾接受比其他病人平均剂量高的乙胺碘呋酮700毫克/天,其他病人为377毫克/天,治疗的平均时间为10.5个月。4例采用沁尿系疗法或者连续乙胺碘呋酮疗法的病人的症状均在10周内消失。但及时停用乙胺碘呋酮的2例患者,泌尿系症状在10天后消失。
According to a research team at the University of Washington in Seattle, epididymitis may be a side effect of ethyiodiridone therapy. A 42-year-old man undergoing amiodarone treatment of ventricular tachycardia left lobar scrotal tenderness and epididymal swelling occurred 11 months after treatment. Urinalysis, urethral aspiration and matched sera did not reveal the cause of the infection, and genitourinary urology was not anatomically abnormal. The symptoms gradually disappear, but the patient died of cardiovascular disease. Epididymal fibrosis and lymphocytic infiltration were also found after death. In addition, the team examined 56 consecutive patients taking amiodarone, in which 6 (11%) had scrotal pain with epididymal swelling lasting more than 6 months Rate is higher than expected. The mean age of 6 patients was the same as that of the other patients, with no anatomical or infectious cause, but they received 700 mg / day of amiodarone higher than the average for other patients and 377 mg / day for other patients, with an average treatment rate The time is 10.5 months. The symptoms of 4 patients treated with urethritis or continuous amiodarone therapy disappeared within 10 weeks. However, two patients who discontinued amiodarone in a timely manner disappeared after 10 days.