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目的探讨冠脉造影显示冠脉临界病变的急性冠脉综合征患者斑块性质与血管重构关系的血管内超声研究。方法对于冠脉造影显示冠脉狭窄病变程度在40%~70%的急性冠脉综合征患者同时行IVUS检查,入选患者94例,行临床基线资料采集、IVUS测量数据,根据重构指数(RI)分组,RI>1为正性重构组,RI<1为负性重构组,RI=1为无重构组。结果软斑块在正性重构组(20例)的比例明显高于负性重构(7例)及无重构组(2例),差异有统计学意义(P<0.05);钙化斑块在负性重构组(15例)的比例明显高于正性重构(5例)及无重构组(2例),差异有统计学意义(P<0.01);正性重构组最小管腔面积处的EEM明显大于其余2组,差异有统计学意义(P<0.05)。结论血管正性重构病变部位更多为软斑块,钙化斑块较少,负性重构则相反。
Objective To investigate the relationship between plaque features and vascular remodeling in patients with acute coronary syndromes undergoing coronary angiography coronary angiography. Methods A total of 94 patients were enrolled in the study. The patients underwent coronary angiography with coronary artery disease (ACS) with 40% -70% severity of coronary artery stenosis. The clinical baseline data and IVUS measurement data were collected. According to the reconstruction index ), RI> 1 is positive reconstruction group, RI <1 is negative reconstruction group, RI = 1 is non-reconstruction group. Results The percentage of soft plaque in positive reconstructive group (20 cases) was significantly higher than that in negative reconstructed group (7 cases) and non-reconstructed group (2 cases), with significant difference (P <0.05) The proportion of block in negative reconstruction group (15 cases) was significantly higher than positive reconstruction (5 cases) and no reconstruction group (2 cases), the difference was statistically significant (P <0.01); positive reconstruction group The EEM at the smallest luminal area was significantly larger than the other two groups, with a statistically significant difference (P <0.05). Conclusion The positive vascular remodeling sites are more soft plaque, less calcified plaque and negative reconstruction.