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A novel poly(N-isopropylacrylamide)-based sandwich-typed hydrogel,which was featured with both ends of linear poly(N-isopropylacrylamide)(PNIPAM)chains being grafted onto cross-linked PNIPAM chains,was successfully prepared in a three-step process by a method of sequential synthesis.The proposed hydrogel displays faster and hydration/dehydration dynamic response to temperature cycling owing to linear PNIPAM chains to form big-pore structure.This work may lead to high attraction for targeting drug delivery systems,polymeric pump,sensors and so on.
A novel poly (N-isopropylacrylamide) -based sandwich-typed hydrogel, which was featured with both ends of linear poly (N-isopropylacrylamide) (PNIPAM) chains being grafted onto a cross-linked PNIPAM chains, was successfully prepared in a three-step process by a method of sequential synthesis. proposed hydrogel displays faster and hydration / dehydration dynamic response to temperature cycling due to to linear PNIPAM chains to form big-pore structure. This work may lead to high attraction for targeting drug delivery systems, polymeric pump, sensors and so on.