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因高血压病而采用肼苯哒嗪治疗可以发生:(1)潮红、头痛、心悸和心肌缺血的心电图改变;(2)风湿综合征;(3)周围神经病变。最近有三篇关于肼苯哒嗪治疗可能引起肝损伤的报道,至今才有4例。本文报道另外3例。这3例患者分别于每日服用脐苯哒嗓50mg2个月、90mg 10个月及60mg2年后出现食欲不振、乏力、肝功能异常而住院。以往无肝病史、无输血或饮酒史。例1和例2有黄疽,肝
Treatment with hydralazine due to hypertension can occur: (1) electrocardiographic changes of flushing, headache, palpitations and myocardial ischemia; (2) rheumatic syndrome; and (3) peripheral neuropathy. There are only three recent reports of hydralazine treatment that may cause liver damage. This article reports the other three cases. The three patients were treated with umbilical cord throat 50 mg for 2 months, 90 mg for 10 months and 60 mg 2 years later, respectively, and were hospitalized for fatigue, liver dysfunction. No past history of liver disease, no history of blood transfusion or alcohol consumption. Cases 1 and 2 had jaundice and liver