论文部分内容阅读
通过报道1例典型的月经前哮喘(PMA),结合复习相关文献,讨论PMA的患病率、发病机制和治疗。40%左右女性哮喘患者月经前出现哮喘加重,但经平喘治疗后仍每次月经前均发作或加重的典型PMA仍少见,PMA的发病机制尚不清楚,可能与体内性激素改变有关,其治疗除哮喘防治指南中常用药物外还包括白三烯调节剂、黄体酮肌肉注射、口服避孕药、促性腺激素释放激素类似物等甚至包括双侧卵巢切除等,国外多种特殊治疗疗效不一,缺乏大量临床实验,所以有待更多相关研究。
By reporting a case of typical premenstrual asthma (PMA), combined with the review of relevant literature to discuss the prevalence of PMA, pathogenesis and treatment. About 40% of female patients with asthma experiencing asthma exacerbations before menstruation, but still after each episode of exacerbation are still rare, but the pathogenesis of PMA is not yet clear, may be related to changes in the body of sex hormones, and its treatment In addition to commonly used drugs in asthma prevention and control guidelines include leukotriene modulator, intramuscular injection of progesterone, oral contraceptives, gonadotropin-releasing hormone analogues and even including bilateral ovariectomy and so on, a variety of special treatment abroad, Lack of a large number of clinical trials, so more relevant research.