论文部分内容阅读
目的探讨不同类型脑卒中患者血脂水平与疾病严重程度的相关性。方法检测260例入院时病程<24 h的脑卒中患者血脂水平,按病情分为出血性脑卒中组160例与缺血性脑卒中组100例;比较患者的血脂水平及其疾病严重程度在不同卒中类型的关系。结果出血性脑卒中血清总胆固醇(TC)、血清甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平、疾病严重程度评分明显低于缺血性脑卒中患者。低TC患者入院24 h内神经功能缺损评分(SSS评分)明显低于血清TC≥6.00 mmo L/L,低TG患者SSS评分明显低于血清TG>12.0 mmol/L的患者(P<0.01)。脑卒中类型、TC及LDL-C水平与SSS评分密切相关,且TC和LDL-C与SSS评分呈正相关。结论病情较严重的脑卒中患者急性期血脂水平较低;脑卒中类型、TC和LDL-C可能是预测急性脑卒中疾病严重程度独立变量。
Objective To investigate the correlation between the level of blood lipids and the severity of disease in different types of stroke patients. Methods The blood lipid levels of 260 stroke patients who were admitted to the hospital at the time of <24 h were measured. According to the disease, 160 patients were divided into hemorrhagic stroke group and 100 ischemic stroke group. The blood lipid levels and the severity of the disease were compared between the two groups The type of stroke. Results The levels of total cholesterol (TC), serum triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and severity of disease in hemorrhagic stroke were significantly lower than those in ischemic stroke. The neurological deficit score (SSS score) in patients with low TC within 24 h was significantly lower than that in patients with serum TC ≥6.00 mmo L / L, and SSS scores in patients with low TG were significantly lower than those in patients with serum TG> 12.0 mmol / L (P <0.01). Stroke types, TC and LDL-C levels were closely related to SSS scores, and TC and LDL-C were positively correlated with SSS scores. Conclusions Stroke patients with more serious illness have lower blood lipid levels in acute phase. The types of stroke, TC and LDL-C may be the independent variables to predict the severity of disease in acute stroke.