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在家犬自然吸入染尘获得接近于人体石棉肺病变动物模型的基础上,我们进一步开展了磷酸羟基哌喹对石棉肺纤维化抑制作用的研究,探讨其治疗效果,为临床应用提供实验依据。
Based on the natural inhalation of dust in domestic dogs to obtain animal model of asbestosis-related lung lesions, we further studied the inhibitory effect of hydroxy-piperazine on asbestosis pulmonary fibrosis, and discussed its therapeutic effect and provided experimental evidence for clinical application.