论文部分内容阅读
目的评价降阶梯疗法联合支气管肺泡灌洗术治疗急性脑卒中合并肺部感染的疗效。方法2004年1月至2005年9月南京军区福州总医院神经内科将82例急性脑卒中合并肺部感染患者随机分成两组。治疗组40例,采用抗菌药物降阶梯疗法联合支气管肺泡灌洗术治疗;对照组42例,采用常规抗菌药物治疗。分别观察其临床疗效、细菌清除率、肺部感染吸收天数、入住神经科重症监护病房(NICU)天数。结果治疗组的有效率及细菌清除率明显高于对照组(P<0.05),而平均肺部感染吸收时间和平均住NICU时间明显少于对照组(P<0.01)。结论以降阶梯疗法联合支气管肺泡灌洗术为基础的局部与全身抗生素联合治疗策略,是治疗急性脑卒中患者合并肺部感染的有效方法。
Objective To evaluate the efficacy of combined descending ladder therapy and bronchoalveolar lavage in the treatment of acute stroke complicated with pulmonary infection. METHODS: From January 2004 to September 2005, 82 patients with acute stroke complicated with lung infection were randomly divided into two groups: Department of Neurology, Fuzhou General Hospital, Nanjing Military Command. Forty patients in the treatment group were treated with anti-bacterial anti-bacteria therapy combined with bronchoalveolar lavage. In the control group, 42 patients were treated with conventional antimicrobial agents. The clinical efficacy, bacterial clearance rate, the days of lung infection absorption, the number of days admitted to the neurological intensive care unit (NICU) were observed. Results The effective rate and bacterial clearance in the treatment group were significantly higher than those in the control group (P <0.05). However, the average pulmonary infection absorption time and average NICU time in the treatment group were significantly less than those in the control group (P <0.01). Conclusions The combined local and systemic antibiotic strategy based on the combination of descending ladder therapy and bronchoalveolar lavage is an effective method for the treatment of acute pulmonary stroke complicated with pulmonary infection.