目的:探讨组合型人工肾(HP/HD)在治疗血液透析患者肾性贫血中的临床疗效。方法:将60例行持续性血透超过1年的患者按照奇偶数字法随机地均分为对照组与观察组,分别采用组合型人工肾(HP/HD)治疗及仅采用维持性HD治疗。比较两组治疗前后血红蛋白(Hb)、红细胞压积(Hct)、血β2微球蛋白(β2MG)、全段甲状旁腺激素(iPTH)及血清铁蛋白(SF)水平变化情况。结果:两组治疗前后Hb、Hct、β2MG、iPTH及SF水平差异均具有统计意义(P<0.05~0.01),且两组治疗后上述指标水平差异均具有统计学意义(P<0.05)。结论:相比于单纯HD治疗,组合型人工肾(HP/HD)治疗血透患者肾性贫血的疗效更为显著。 Objective: To investigate the clinical efficacy of combined artificial kidney (HP / HD) in the treatment of renal anemia in hemodialysis patients. Methods: Sixty patients undergoing continuous hemodialysis for more than one year were randomly divided into control group and observation group according to the parity digit method. The patients were treated with combined artificial kidney (HP / HD) and only with maintenance HD. The changes of hemoglobin (Hb), hematocrit (Hct), β2 microglobulin (β2MG), iPTH and SF of the two groups were compared before and after treatment. Results: The levels of Hb, Hct, β2MG, iPTH and SF before and after treatment in both groups were statistically significant (P <0.05 ~ 0.01). There was significant difference in the above indexes between the two groups after treatment (P <0.05). CONCLUSIONS: Combined hemodialysis (HP / HD) is more effective in treating renal anemia in hemodialysis patients than in HD alone.