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我院1993年6月至1994年5月采用抗乙肝免疫核糖核酸(IRNA)治疗乙型慢性活动型肝炎64例,并重点观察了HBV血清学标志的变化,结果表明抗乙肝IRNA对HBV复制有较好的抑制作用,现报道如下。 1 临床资料 1.1 病例选择:按1990年上海全国病毒性肝炎会议诊断标准,选择住院的乙型慢性活动型肝炎(CAH)96例,随机分为①治疗组64例,其中男62例,女2例,年龄17—52岁,平均38.8岁,病程平均2.12年。②对照组32例,其中男31例,女1例,年龄
Our hospital from June 1993 to May 1994 with anti-hepatitis B immune RNA (IRNA) treatment of chronic active hepatitis B 64 cases, and the focus of the observation of HBV serological markers of change, the results show that anti-hepatitis B IRNA replication of HBV with Better inhibition, are reported below. 1 Clinical data 1.1 Case Selection: 96 cases of chronic hepatitis B (CAH) hospitalized in accordance with the diagnostic criteria of the National Shanghai Hepatitis Conference in 1990, were randomly divided into ① treatment group of 64 cases, 62 males and 2 females Cases, aged 17-52 years, mean 38.8 years old, duration of an average of 2.12 years. ② control group of 32 patients, 31 males and 1 female, age