灭滴灵于1960年开始应用临床,1962年Shinn开始用于厌氧菌治疗。但用它治疗脓胸的报导尚少,现将我院用于灭滴灵治疗厌氧菌感染脓胸特报告如下: 病例介绍:本组六例患者均为男性,年令在23—68岁之间。发病均有高热、体温在39℃以上。全身乏力不适等急性感染的症状。咳大量脓血性臭痰。有胸腔积液的症状及体征,血白细胞多在19000—32400/mm~3之间,核左移。X线检查见胸腔积液。胸腔闭式引流术引出大量恶臭脓汁(350—1300cc左右)。呈灰白色粘稠状,具有恶臭味。术后每日引流量亦在200ml左右。入院后均用青·链·卡那·庆大·红霉素等常用抗菌素治疗而无效。改用氨基苯、羧基苯青霉素后亦未凑效。从而改用灭滴灵治疗。其量根据 Metronidazole began clinical application in 1960, and in 1962 Shinn began to be used for anaerobic treatment. However, the treatment of empyema with its reports are still small, now our hospital for metronidazole treatment of anaerobic infections pus special report as follows: Case Description: This group of six patients were male, the year at 23-68 years old between. The incidence of fever, body temperature above 39 ℃. Fatigue and other symptoms of acute infection. Cough a large number of purulent bloody sputum. There are symptoms and signs of pleural effusion, white blood cells more than 19000-32400 / mm ~ 3, the left core shift. X-ray examination see pleural effusion. Closed thoracic drainage leads to a large number of stinking pus juice (350-1300cc or so). Gray-white viscous, with foul odor. Postoperative daily drainage is also about 200ml. After admission, they were treated with commonly used antibiotics, such as Green Chain, Kana, Big Blue, and Erythromycin. Switch to aminobenzene, carboxybenzene penicillin did not work after. To switch to metronidazole treatment. The amount according to