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目的 :为了探讨肌钙蛋白 I(c Tn I)、肌红蛋白 (Mb)定量检测对急性心肌梗塞 (AMI)患者因缺血、缺氧所引起的心肌坏死面积大小的临床价值。方法 :健康对照组 6 0例 ,于 9:0 0空腹抽静脉血 3ml,AMI组于胸痛发作后分 3、6、9、12 h抽静脉血 3ml,采用全自动微粒子化学发光分析仪定量检测 c Tn I Mb。结果 :AMI组 c Tn I Mb于胸痛 3h后随时间增加而逐步增高 ,与正常对照组有显著差异 (P<0 .0 1)。结论 :当 c Tn I>0 .5μg/ L时确定为 AMI。c Tn I Mb增高越显著 ,心梗程度越深 ,心肌因缺血、缺氧而坏死的面积就越大。
Objective: To investigate the clinical value of quantitative detection of cTn I and Mb in myocardial infarction area caused by ischemia and hypoxia in patients with acute myocardial infarction (AMI). Methods: The healthy control group 60 cases, fasting venous blood 3ml at 9: 0 0, AMI group 3ml blood venous blood 3,6,9,12 h after the onset of chest pain, using automated particle chemiluminescence analyzer quantitative detection c Tn I Mb. Results: In the AMI group, cTnI Mb gradually increased with time after 3 hours of chest pain, which was significantly different from that of the normal control group (P <0.01). Conclusions: AMI was identified when c Tn I> 0.5 μg / L. c TnI Mb increased significantly more significant myocardial infarction the deeper the myocardial ischemia, hypoxia and necrosis of the larger the area.