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目的:研究亲属活体肾移植术后早期不同脂质水平对移植肾功能的影响。方法:回顾性分析2014年1月1日至2016年1月1日在郑州人民医院器官移植中心进行亲属活体肾移植的60例受体的临床资料,收集术后6个月、12个月受体的血脂情况和移植肾功能,根据肾小球滤过率(GFR)中国人公式计算GFR,分别计算甘油三酯/高密度脂蛋白(TG/HDL)、总胆固醇/高密度脂蛋白(TC/HDL)、低密度脂蛋白/高密度脂蛋白(LDL/HDL)的比值进行统计。结果:术后6个月和12个月时,TG/HDL分别为1.54±0.72、2.10±1.77,差异具有统计学意义(n P0.05)相关。n 结论:亲属活体肾移植术后早期血脂水平与GFR呈负相关,是影响早期移植肾功能的一个重要危险因素。“,”Objective:To observe the correlation of the lipid profile on early function of living donor’s transplanted kidney.Methods:Clinical data of 60 cases of recipients undergoing living related renal transplantation were retrospectively analyzed. Lipid profile and serum creatine were collected. Estimated glomerular filtration (GFD) rate of recipients was calculated according to Chinese formula. TG/HDL, TC/HDL, LDL/HDL were also calculated. The correlation between lipid profile and GFR was analyzed by SPSS 16.0 software, and n P0.05).n Conclusions:There was negative correlation of lipid profile and GFR, TC had more exert on GFR in the earlier stage, and TG had more exert on GFR in the later stage. Therefore, lipid profile of TC and TG might be a risk factor of decreased allograft function.