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~(99m)Tc 标记的胆道显像剂广泛地用于胆囊功能的研究,然而对于胆囊收缩功能的研究颇多,对胆囊充盈功能的研究则甚少,各学者应用缩胆囊素及其同类药物的剂量及给药方法也不同。本文就胆囊功能及胆囊排空动力学加以研究,并探讨8肽缩胆囊素(OP-CCK)的最佳给药剂量与方法。22例肝功能试验正常,并经口服药物法行胆囊造影与超声波显像证实无胆结石的男性病人,平均年龄55.8(33～69岁)岁;平均身高1.76(1.68～1.84米)米;平均体重81.7(62.1～100.7公斤)公斤。前一天晚上禁食,取仰卧位,γ相机采用针孔型准直器,静脉注射~(99m)Tc-Disofenin 0.5～1.0mCi,1帧/分,连续
~ (99m) Tc-labeled biliary imaging agent is widely used in the study of gallbladder function, however, there are many studies on the function of gallbladder contraction and few studies on the filling function of gallbladder. All scholars apply cholecystokinin and its similar drugs The dosage and method of administration are also different. In this paper, we studied the function of gallbladder and the dynamics of gallbladder emptying, and explored the best dosage and method of OP-CCK. 22 cases of normal liver function tests and oral administration of gallbladder and ultrasound imaging confirmed gallbladder-free male patients, the average age of 55.8 (33 to 69 years) years of age; the average height of 1.76 (1.68 to 1.84 meters) Weight 81.7 (62.1 ~ 100.7 kg) kg. The night before fasting, supine, gamma camera using a pinhole collimator, intravenous ~ (99m) Tc-Disofenin 0.5 ~ 1.0mCi, 1 frame / min, continuous