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[目的]观察手机频段(900MHz)微波辐射对小鼠头部表面温度、非空间学习记忆能力和对外界环境兴奋性的影响。[方法]采用900MHz、90μW/cm2微波辐照小鼠2h,于辐照前、辐照中不同时间点和辐照后20min测量小鼠头部表面温度。避暗反应和开放场实验中,将小鼠随机分为3组:对照组,一次微波辐射组(功率密度90μW/cm2、辐照1h),持续微波辐射组(功率密度90μW/cm2、1h/d、持续辐照10d);比较微波辐射不同时间后小鼠学习记忆能力和对外界环境兴奋性的不同。[结果]辐射组小鼠随着辐照时间的延长,头部表面温度逐渐升高;在辐照100min时达最高点,与辐照前相比升高(2.95±0.48)℃;此后温度有所下降,但仍明显高于对照组(P<0.01)。避暗实验中,一次微波辐射组与持续微波辐射组接受不同时间辐照后的潜伏期、错误次数差异均无统计学意义。开放场实验中,一次微波辐射组,辐照30min后较辐照前活动时间减少(P<0.05),停止辐照后30min的活动时间仍减少(P<0.05);持续微波辐射组,辐照6d后较辐照前小鼠总路程增加(P<0.05),平均速度增加(P<0.01),休息时间减少(P<0.05)。[结论]900MHz、90μW/cm2微波辐射对小鼠可能存在热效应;一次微波辐射和持续微波辐射,一定程度上影响了小鼠对外界环境的兴奋性,但对小鼠非空间学习记忆能力无明显影响。
[Objective] To observe the effect of mobile phone frequency band (900MHz) microwave radiation on mouse head surface temperature, non-spatial learning and memory ability and excitability to external environment. [Method] The mice were irradiated with 900MHz and 90μW / cm2 microwaves for 2h. The temperature of the mouse head surface was measured before irradiation, at different time points and at 20min after irradiation. The mice were randomly divided into 3 groups: control group, primary microwave irradiation group (power density 90μW / cm2, irradiation 1h), continuous microwave irradiation group (power density 90μW / cm2, 1h / d, continuous irradiation 10d). Compared the mice’s learning and memory abilities and the excitability of the external environment after different periods of microwave radiation. [Result] The temperature of the head surface increased gradually with the irradiation time prolonged in irradiation group mice, reaching the highest point at 100 min after irradiation and increased by 2.95 ± 0.48 ℃ compared with that before irradiation Decreased, but still significantly higher than the control group (P <0.01). In the dark-avoidance experiment, there was no significant difference in the latency and the number of errors between the microwave irradiation group and the continuous microwave irradiation group after receiving different time of irradiation. In the open field experiment, the activity time of the microwave radiation group was decreased 30 min after irradiation (P <0.05), and the activity time was still decreased 30 min after the irradiation was stopped (P <0.05). In the continuous microwave irradiation group, After 6 days, the total distance of mice before irradiation increased (P <0.05), the average speed increased (P <0.01), and the resting time decreased (P <0.05). [Conclusion] The thermal effects of 900MHz and 90μW / cm2 microwave radiation on mice may exist. One time microwave irradiation and continuous microwave radiation may affect the excitability of mice to the outside world to some extent, but there is no obvious effect on the non-spatial learning and memory ability of mice influences.