论文部分内容阅读
目的探讨血浆同型半胱氨酸水平与急性胰腺炎的关系。方法 160例急性胰腺炎患者,测定其血浆同型半胱氨酸(homocysteine,Hcy)、三酰甘油(triacylglycerol,TG)、总胆固醇(total cholesterol,TC)、高密度脂蛋白胆固醇(high density lipoprotein-cholesterol,HDL-C)、低密度脂蛋白胆固醇(low density lipoprotein-cholesterol,LDL-C)水平,并依据血浆Hcy水平分为观察组(血浆Hcy>15μmol/L)75例和对照组(血浆Hcy水平5~15μmol/L)85例,比较2组TG、TC、HDL-C、LDL-C水平及高胆固醇血症、高甘油三酯血症发生率。结果观察组TG[(3.0±2.0)mmol/L]、TC[(4.7±1.8)mmol/L]水平低于对照组[(4.6±2.4)、(5.5±2.9)mmol/L](P<0.05),HDL-C[(1.1±0.5)mmol/L]、LDL-C[(2.8±1.3)mmol/L]与对照组[(1.3±1.0)、(2.9±1.6)mmol/L]比较差异无统计学意义(P>0.05);观察组高胆固醇血症、高甘油三酯血症发生率(25.3%、48.0%)低于对照组(64.7%、65.9%)(P<0.05)。结论高血浆Hcy水平可能与急性胰腺炎有关。
Objective To investigate the relationship between plasma homocysteine level and acute pancreatitis. Methods Totally 160 patients with acute pancreatitis were divided into two groups according to their plasma levels of homocysteine (Hcy), triacylglycerol (TG), total cholesterol (TC), high density lipoprotein- (HDL-C) and low density lipoprotein-cholesterol (LDL-C) in the observation group were divided into observation group (Hcy> 15μmol / L) 75 cases and control group Level 5 ~ 15μmol / L) 85 cases, compared two groups TG, TC, HDL-C, LDL-C levels and hypercholesterolemia, the incidence of hypertriglyceridemia. Results The levels of TG [(3.0 ± 2.0) mmol / L] and TC [(4.7 ± 1.8) mmol / L] in the observation group were significantly lower than those in the control group [(4.6 ± 2.4) vs 0.05), HDL-C [(1.1 ± 0.5) mmol / L] and LDL-C [(2.8 ± 1.3) mmol / L] compared with those in control group [(1.3 ± 1.0), (2.9 ± 1.6) mmol / L] The difference was not statistically significant (P> 0.05). The incidence of hypercholesterolemia and hypertriglyceridemia in the observation group (25.3%, 48.0%) was lower than that in the control group (64.7%, 65.9%) (P <0.05). Conclusion High plasma Hcy levels may be related to acute pancreatitis.