无创正压机械通气(noninvasive positive-pressure ventila-tion,NPPV)应用于慢性阻塞性肺病急性加重期(acute exacerba-tion of chronic obstructive pulmonary disease,AECOPD)伴呼吸衰竭的治疗,可取得较好疗效,但NPPV有其自身的局限性[1]。我科2005年1月至2009年1月应用NPPV The application of noninvasive positive-pressure ventilation (NPPV) in the treatment of acute exacerba- tion of chronic obstructive pulmonary disease (AECOPD) with respiratory failure can achieve better curative effect, But NPPV has its own limitations [1]. Our department from January 2005 to January 2009 the application of NPPV