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目的观察纳洛酮联合去乙酰毛花苷注射液(西地兰)治疗婴儿肺炎合并心力衰竭的临床效果。方法 200例肺炎合并心力衰竭患儿,根据治疗方案不同分为对照组A(60例)、对照组B(60例)及观察组(80例)。对照组A采用纳洛酮治疗方案,对照组B采用西地兰治疗方案,观察组采用纳洛酮联合西地兰治疗方案,对比三组患儿的治疗效果。结果对照组A患儿治疗总有效率为80.0%(其中显效20例,有效28例,无效12例),对照组B为78.3%(其中显效18例,有效29例,无效13例),观察组为92.5%(其中显效30例,有效44例,无效6例),前两组治疗总有效率对比差异无统计学意义(P>0.05),与观察组相比,差异均有统计学意义(P<0.05)。结论采用纳洛酮联合西地兰治疗婴儿肺炎合并心力衰竭疗效确切,临床疗效高于二者单用方案,用药安全方便,不良反应少,值得临床推广应用。
Objective To observe the clinical effect of naloxone and stilbene injection (cedilanid) in the treatment of infantile pneumonia complicated with heart failure. Methods 200 cases of children with pneumonia complicated with heart failure were divided into control group A (60 cases), control group B (60 cases) and observation group (80 cases). Control group A treated with naloxone, control group B treated with cedilanid, observation group treated with naloxone combined with cedilanid, compared the therapeutic effect of three groups of children. Results The total effective rate of treatment group A was 80.0% (20 cases were markedly effective, 28 cases were effective and 12 ineffective), and 78.3% in control group B (18 cases were markedly effective, 29 cases were effective and 13 cases were ineffective) (92.5%), of which 30 were markedly effective, 44 were effective and 6 were ineffective. There was no significant difference in the total effective rate between the two groups (P> 0.05), and the differences were statistically significant (P <0.05). Conclusion Naloxone combined with cedilanid in the treatment of infantile pneumonia complicated with heart failure has definite curative effect. The clinical curative effect is higher than that of the two alone regimens. It is safe and convenient to use and has few adverse reactions. It deserves clinical application.