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据CMJ报道,上海仁济医院鲍春德医师等应用来氟米特双盲对照治疗类风湿性关节炎,结果表明,来氟米特能显著改善类风湿性关节炎病人的临床症状和体征,有效率达90％左右,病人的关节功能及生活质量也有显著提高,来氟米特的不良反应发生率低于对照药甲氨喋呤。主要不良反应包括胃肠道不适,皮疹,脱发及白细胞下降,轻度肝损等。该研究结果将对改善类风湿性关节炎病人的预后有重要意义。
According to CMJ reports, Shanghai Renji Hospital, Dr. Bao Chunde and other applications of leflunomide double-blind control of rheumatoid arthritis, the results show that leflunomide can significantly improve the clinical symptoms and signs of rheumatoid arthritis patients, effective Up to 90%, the patient’s joint function and quality of life also significantly improved, the incidence of adverse reactions leflunomide was lower than the control drug methotrexate. The main adverse reactions include gastrointestinal discomfort, rash, hair loss and leukopenia, mild liver damage and so on. The results of this study will improve the prognosis of patients with rheumatoid arthritis is of great significance.