原发性十二指肠恶性肿瘤临床较少见 ,因其起病隐匿 ,又缺乏典型的临床表现 ,使该病的诊治有一定的难度。我院从 1994～ 1999年收治该类患者 4 3例 (不包括壶腹周围癌 ) ,现根据其临床资料进行回顾性分析 ,以提高对本病的早期诊断及治疗效果。1　临床资料1.1　性别与年龄 :本组 Primary duodenal malignancies are relatively rare clinical, because of its insidious onset, but also the lack of a typical clinical manifestations, the diagnosis and treatment of the disease has a certain degree of difficulty. Our hospital from 1994 to 1999 admitted 43 cases of these patients (not including periampullary cancer), are based on clinical data for retrospective analysis to improve the early diagnosis and treatment of the disease. 1 clinical data 1.1 gender and age: the group